3BLH
Crystal Structure of Human CDK9/cyclinT1
Summary for 3BLH
Entry DOI | 10.2210/pdb3blh/pdb |
Related | 3BLQ 3BLR |
Descriptor | Cell division protein kinase 9, Cyclin-T1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | transcriptional cdk-cyclin complex, phosphorylated, alternative splicing, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, transcription regulation, transferase, acetylation, cell cycle, cell division, coiled coil, host-virus interaction, transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P50750 O60563 |
Total number of polymer chains | 2 |
Total formula weight | 68295.65 |
Authors | Baumli, S.,Lolli, G.,Lowe, E.D.,Johnson, L.N. (deposition date: 2007-12-11, release date: 2008-07-01, Last modification date: 2023-11-01) |
Primary citation | Baumli, S.,Lolli, G.,Lowe, E.D.,Troiani, S.,Rusconi, L.,Bullock, A.N.,Debreczeni, J.E.,Knapp, S.,Johnson, L.N. The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation Embo J., 27:1907-1918, 2008 Cited by PubMed: 18566585DOI: 10.1038/emboj.2008.121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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