3BJU

Crystal Structure of tetrameric form of human lysyl-tRNA synthetase

Summary for 3BJU

Entry DOI	10.2210/pdb3bju/pdb
Descriptor	Lysyl-tRNA synthetase, CALCIUM ION, LYSINE, ... (5 entities in total)
Functional Keywords	trna synthetase, lysyl-trna, aminoacyl-trna synthetase, atp-binding, cytoplasm, ligase, nucleotide-binding, phosphoprotein, polymorphism, protein biosynthesis
Biological source	Homo sapiens (human)
Cellular location	Isoform Cytoplasmic: Cytoplasm, cytosol . Isoform Mitochondrial: Mitochondrion : Q15046
Total number of polymer chains	4
Total formula weight	244343.64
Authors	Guo, M.,Yang, X.L.,Schimmel, P. (deposition date: 2007-12-04, release date: 2008-02-05, Last modification date: 2023-08-30)
Primary citation	Guo, M.,Ignatov, M.,Musier-Forsyth, K.,Schimmel, P.,Yang, X.L. Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation Proc.Natl.Acad.Sci.Usa, 105:2331-2336, 2008 Cited by PubMed: 18272479 DOI: 10.1073/pnas.0712072105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation