3BIM

Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide

Summary for 3BIM

Entry DOI	10.2210/pdb3bim/pdb
Descriptor	B-cell lymphoma 6 protein, BCL-6 corepressor (3 entities in total)
Functional Keywords	protein-peptide compex, activator, chromosomal rearrangement, dna-binding, metal-binding, nucleus, phosphoprotein, polymorphism, proto-oncogene, repressor, transcription, transcription regulation, zinc, zinc-finger, alternative splicing, ank repeat, chromatin regulator, disease mutation, transcription repressor
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : P41182 Q6W2J9
Total number of polymer chains	16
Total formula weight	131903.61
Authors	Prive, G.G.,Ghetu, A.F. (deposition date: 2007-11-30, release date: 2008-01-08, Last modification date: 2023-08-30)
Primary citation	Ghetu, A.F.,Corcoran, C.M.,Cerchietti, L.,Bardwell, V.J.,Melnick, A.,Prive, G.G. Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer. Mol.Cell, 29:384-391, 2008 Cited by PubMed: 18280243 DOI: 10.1016/j.molcel.2007.12.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation