3BIM

Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide

3BIM の概要

• エントリーDOI: 10.2210/pdb3bim/pdb
• 分子名称: B-cell lymphoma 6 protein, BCL-6 corepressor (3 entities in total)
• 機能のキーワード: protein-peptide compex, activator, chromosomal rearrangement, dna-binding, metal-binding, nucleus, phosphoprotein, polymorphism, proto-oncogene, repressor, transcription, transcription regulation, zinc, zinc-finger, alternative splicing, ank repeat, chromatin regulator, disease mutation, transcription repressor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : P41182 Q6W2J9
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 131903.61

構造登録者

Prive, G.G.,Ghetu, A.F. (登録日: 2007-11-30, 公開日: 2008-01-08, 最終更新日: 2023-08-30)

• 主引用文献: Ghetu, A.F.,Corcoran, C.M.,Cerchietti, L.,Bardwell, V.J.,Melnick, A.,Prive, G.G.; Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.; Mol.Cell, 29:384-391, 2008; PubMed: 18280243; DOI: 10.1016/j.molcel.2007.12.026

実験手法

X-RAY DIFFRACTION (2.6 Å)