3BHX
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of Asp-Glu
3BHX の概要
エントリーDOI | 10.2210/pdb3bhx/pdb |
関連するPDBエントリー | 3BI0 3BI1 |
分子名称 | Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
機能のキーワード | prostate specific membrane antigen, metallopeptidase, folate hydrolase, glutamate carboxypeptidase ii, naaladase, dipeptidase, glycoprotein, metal-binding, metalloprotease, multifunctional enzyme, protease, signal-anchor, transmembrane, hydrolase |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm: Q04609 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 83033.07 |
構造登録者 | |
主引用文献 | Barinka, C.,Hlouchova, K.,Rovenska, M.,Majer, P.,Dauter, M.,Hin, N.,Ko, Y.S.,Tsukamoto, T.,Slusher, B.S.,Konvalinka, J.,Lubkowski, J. Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs J.Mol.Biol., 376:1438-1450, 2008 Cited by PubMed: 18234225DOI: 10.1016/j.jmb.2007.12.066 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.6 Å) |
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