3BHL
E.coli thymidylate synthase complexes with 5-NO2dUMP and tetrahydrofolate at 1.4 A resolution
Summary for 3BHL
Entry DOI | 10.2210/pdb3bhl/pdb |
Related | 3B9H 3BFI 3BGX 3BHR |
Descriptor | Thymidylate synthase, 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, (6S)-5,6,7,8-TETRAHYDROFOLATE, ... (5 entities in total) |
Functional Keywords | methyltransferase, nucleotide biosynthesis, repressor, rna-binding, translation regulation, transferase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P0A884 |
Total number of polymer chains | 2 |
Total formula weight | 63008.77 |
Authors | Roberts, S.A.,Montfort, W.R. (deposition date: 2007-11-28, release date: 2008-12-02, Last modification date: 2023-08-30) |
Primary citation | Arendall III, W.B.,Hyatt, D.C.,Roberts, S.A.,Weichsel, A.,Dahlgren, A.L.,Maley, F.,Montfort, W.R. Structural Studies of Early Events in Catalysis by Thymidylate Synthase To be Published, |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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