3BGV

Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH

Summary for 3BGV

• Entry DOI: 10.2210/pdb3bgv/pdb
• Descriptor: mRNA cap guanine-N7 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: methyltransferase, alternative splicing, mrna capping, mrna processing, nucleus, phosphoprotein, rna-binding, s-adenosyl-l-methionine, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O43148
• Total number of polymer chains: 4
• Total formula weight: 148630.49

Authors

Lunin, V.V.,Wu, H.,Zeng, H.,Antoshenko, T.,MacKenzie, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Plotnikov, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2007-11-27, release date: 2007-12-04, Last modification date: 2023-08-30)

• Primary citation: Wu, H.,Lunin, V.V.,Zeng, H.,Antoshenko, T.,MacKenzie, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Plotnikov, A.N.; The crystal structure of human RNA (guanine-7-) methyltransferase in complex with SAH.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)