3BGS
Structure of human purine nucleoside phosphorylase with L-DADMe-ImmH and phosphate
Summary for 3BGS
Entry DOI | 10.2210/pdb3bgs/pdb |
Related | 1RR6 1RSZ 1RT9 |
Descriptor | purine nucleoside phosphorylase, PHOSPHATE ION, 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, ... (4 entities in total) |
Functional Keywords | pnp, transition state analogue, l-enantiomer, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 32735.08 |
Authors | Murkin, A.S.,Ramagopal, U.A.,Almo, S.C.,Schramm, V.L. (deposition date: 2007-11-27, release date: 2008-01-08, Last modification date: 2023-08-30) |
Primary citation | Rinaldo-Matthis, A.,Murkin, A.S.,Ramagopal, U.A.,Clinch, K.,Mee, S.P.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase J.Am.Chem.Soc., 130:842-844, 2008 Cited by PubMed: 18154341DOI: 10.1021/ja710733g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.099 Å) |
Structure validation
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