3BA0

Crystal structure of full-length human MMP-12

Summary for 3BA0

Entry DOI	10.2210/pdb3ba0/pdb
Related	1SU3
Descriptor	Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	full-length mmp-12, hemopexin domain, catalytic domain, domain interaction., calcium, extracellular matrix, glycoprotein, hydrolase, metal-binding, metalloprotease, polymorphism, protease, secreted, zinc, zymogen
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	42509.54
Authors	Bertini, I.,Calderone, V.,Fragai, M.,Jaiswal, R.,Luchinat, C.,Melikian, M.,Myonas, E.,Svergun, D.I. (deposition date: 2007-11-07, release date: 2008-07-29, Last modification date: 2023-11-01)
Primary citation	Bertini, I.,Calderone, V.,Fragai, M.,Jaiswal, R.,Luchinat, C.,Melikian, M.,Mylonas, E.,Svergun, D.I. Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12. J.Am.Chem.Soc., 130:7011-7021, 2008 Cited by PubMed: 18465858 DOI: 10.1021/ja710491y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation