3B9F

1.6 A structure of the PCI-thrombin-heparin complex

Summary for 3B9F

Entry DOI	10.2210/pdb3b9f/pdb
Related	2HI9 2OL2
Descriptor	Prothrombin, Plasma serine protease inhibitor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	michaelis complex, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	81646.57
Authors	Li, W.,Adams, T.E.,Huntington, J.A. (deposition date: 2007-11-05, release date: 2008-04-22, Last modification date: 2023-11-01)
Primary citation	Li, W.,Adams, T.E.,Nangalia, J.,Esmon, C.T.,Huntington, J.A. Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex. Proc.Natl.Acad.Sci.Usa, 105:4661-4666, 2008 Cited by PubMed: 18362344 DOI: 10.1073/pnas.0711055105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation