3B9F

1.6 A structure of the PCI-thrombin-heparin complex

3B9F の概要

• エントリーDOI: 10.2210/pdb3b9f/pdb
• 関連するPDBエントリー: 2HI9 2OL2
• 分子名称: Prothrombin, Plasma serine protease inhibitor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: michaelis complex, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 81646.57

構造登録者

Li, W.,Adams, T.E.,Huntington, J.A. (登録日: 2007-11-05, 公開日: 2008-04-22, 最終更新日: 2023-11-01)

• 主引用文献: Li, W.,Adams, T.E.,Nangalia, J.,Esmon, C.T.,Huntington, J.A.; Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.; Proc.Natl.Acad.Sci.Usa, 105:4661-4666, 2008; PubMed: 18362344; DOI: 10.1073/pnas.0711055105

実験手法

X-RAY DIFFRACTION (1.6 Å)