3B7J
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) from Helicobacter pylori complexed with juglone
Summary for 3B7J
Entry DOI | 10.2210/pdb3b7j/pdb |
Related | 2GLL 2GLM 2GLP 2GLV |
Descriptor | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ... (5 entities in total) |
Functional Keywords | fabz complex, juglone, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase |
Biological source | Helicobacter pylori (Campylobacter pylori) |
Cellular location | Cytoplasm (By similarity): Q5G940 |
Total number of polymer chains | 6 |
Total formula weight | 110638.80 |
Authors | Zhang, L.,Kong, Y.H.,Wu, D.,Shen, X.,Jiang, H.L. (deposition date: 2007-10-31, release date: 2008-09-02, Last modification date: 2023-11-01) |
Primary citation | Kong, Y.H.,Zhang, L.,Yang, Z.Y.,Han, C.,Hu, L.H.,Jiang, H.L.,Shen, X. Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization ACTA PHARMACOL.SIN., 29:870-876, 2008 Cited by PubMed: 18565285DOI: 10.1111/j.1745-7254.2008.00808.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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