3B54

Saccharomyces cerevisiae nucleoside diphosphate kinase

3B54 の概要

• エントリーDOI: 10.2210/pdb3b54/pdb
• 分子名称: Nucleoside diphosphate kinase, PHOSPHATE ION (3 entities in total)
• 機能のキーワード: alpha/beta sandwich, atp-binding, kinase, magnesium, metal-binding, mitochondrion, nucleotide metabolism, nucleotide-binding, phosphorylation, transferase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• 細胞内の位置: Cytoplasm: P36010
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36607.55

構造登録者

Wang, H.B.,Bao, R.,Cheng, Y.X. (登録日: 2007-10-25, 公開日: 2008-10-07, 最終更新日: 2023-11-01)

主引用文献

Wang, H.,Bao, R.,Jiang, C.,Yang, Z.,Zhou, C.-Z.,Chen, Y.
Structure of Ynk1 from the yeast Saccharomyces cerevisiae
Acta Crystallogr.,Sect.F, 64:572-576, 2008

PubMed Abstract: Nucleoside diphosphate kinase (NDPK) catalyzes the transfer of the gamma-phosphate from nucleoside triphosphates to nucleoside diphosphates. In addition to biochemical studies, a number of crystal structures of NDPK from various organisms, including both native proteins and complexes with nucleotides or nucleotide analogues, have been determined. Here, the crystal structure of Ynk1, an NDPK from the yeast Saccharomyces cerevisiae, has been solved at 3.1 A resolution. Structural analysis strongly supports the oligomerization state of this protein being hexameric rather than tetrameric.

PubMed: 18607079
DOI: 10.1107/S1744309108015212

実験手法

X-RAY DIFFRACTION (3.1 Å)