3B4V
X-Ray structure of Activin in complex with FSTL3
Summary for 3B4V
Entry DOI | 10.2210/pdb3b4v/pdb |
Descriptor | Inhibin beta A chain, follistatin-like 3, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | ligand-inhibitor signalling complex, cleavage on pair of basic residues, glycoprotein, growth factor, hormone, secreted, nucleus, proto-oncogene, hormone regulator complex |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 152645.57 |
Authors | Thompson, T.B. (deposition date: 2007-10-24, release date: 2008-09-02, Last modification date: 2020-07-29) |
Primary citation | Stamler, R.,Keutmann, H.T.,Sidis, Y.,Kattamuri, C.,Schneyer, A.,Thompson, T.B. The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity. J.Biol.Chem., 283:32831-32838, 2008 Cited by PubMed: 18768470DOI: 10.1074/jbc.M801266200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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