3B4V

X-Ray structure of Activin in complex with FSTL3

3B4V の概要

• エントリーDOI: 10.2210/pdb3b4v/pdb
• 分子名称: Inhibin beta A chain, follistatin-like 3, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: ligand-inhibitor signalling complex, cleavage on pair of basic residues, glycoprotein, growth factor, hormone, secreted, nucleus, proto-oncogene, hormone regulator complex
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 152645.57

構造登録者

Thompson, T.B. (登録日: 2007-10-24, 公開日: 2008-09-02, 最終更新日: 2020-07-29)

• 主引用文献: Stamler, R.,Keutmann, H.T.,Sidis, Y.,Kattamuri, C.,Schneyer, A.,Thompson, T.B.; The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.; J.Biol.Chem., 283:32831-32838, 2008; PubMed: 18768470; DOI: 10.1074/jbc.M801266200

実験手法

X-RAY DIFFRACTION (2.48 Å)