3AYC

Crystal structure of galectin-3 CRD domian complexed with GM1 pentasaccharide

3AYC の概要

• エントリーDOI: 10.2210/pdb3ayc/pdb
• 関連するPDBエントリー: 3AYA 3AYD 3AYE
• 分子名称: Galectin-3, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: rossmann fold, a beta-galactose-binding protein, beta-galactosides, cell-surface, nuclear, sugar binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32546.92

構造登録者

Bian, C.F.,Li, D.F.,Wang, D.C. (登録日: 2011-05-04, 公開日: 2011-10-12, 最終更新日: 2023-11-01)

• 主引用文献: Bian, C.F.,Zhang, Y.,Sun, H.,Li, D.F.,Wang, D.C.; Structural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen; Plos One, 6:e25007-e25007, 2011; PubMed: 21949831; DOI: 10.1371/journal.pone.0025007

実験手法

X-RAY DIFFRACTION (1.8 Å)