3AY8

Glutathione S-transferase unclassified 2 from Bombyx mori

Summary for 3AY8

Entry DOI	10.2210/pdb3ay8/pdb
Descriptor	Glutathione S-transferase, GLYCEROL (3 entities in total)
Functional Keywords	gst fold, transfer, gst binding, cytosolic, transferase
Biological source	Bombyx mori (silk moth, silkworm)
Total number of polymer chains	1
Total formula weight	24577.23
Authors	Kakuta, Y.,Usuda, K.,Nakashima, T.,Kimura, M.,Aso, Y.,Yamamoto, K. (deposition date: 2011-05-02, release date: 2011-09-07, Last modification date: 2023-11-01)
Primary citation	Kakuta, Y.,Usuda, K.,Nakashima, T.,Kimura, M.,Aso, Y.,Yamamoto, K. Crystallographic survey of active sites of an unclassified glutathione transferase from Bombyx mori Biochim.Biophys.Acta, 1810:1355-1360, 2011 Cited by PubMed Abstract: Glutathione transferase (GST) catalyzes a major step in the xenobiotic detoxification pathway. We previously identified a novel, unclassified GST that is upregulated in an insecticide-resistant silkworm (Bombyx mori) upon insecticide exposure. Here, we sought to further characterize this GST, bmGSTu, by solving and refining its crystal structure and identifying its catalytic residues. PubMed: 21756974 DOI: 10.1016/j.bbagen.2011.06.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation