3ASJ
Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
Summary for 3ASJ
| Entry DOI | 10.2210/pdb3asj/pdb |
| Descriptor | Homoisocitrate dehydrogenase, 3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
| Functional Keywords | beta-hydroxy acid oxidative decarboxylase, lysine biosynthesis, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Thermus thermophilus |
| Total number of polymer chains | 4 |
| Total formula weight | 146649.11 |
| Authors | Nango, E.,Kumasaka, T.,Eguchi, T. (deposition date: 2010-12-13, release date: 2011-09-21, Last modification date: 2023-11-01) |
| Primary citation | Nango, E.,Yamamoto, T.,Kumasaka, T.,Eguchi, T. Structure of Thermus thermophilus homoisocitrate dehydrogenase in complex with a designed inhibitor J.Biochem., 150:607-614, 2011 Cited by PubMed: 21813504DOI: 10.1093/jb/mvr097 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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