3ASJ
Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Homoisocitrate dehydrogenase | polymer | 334 | 35967.3 | 4 | UniProt (Q8RQU4) Pfam (PF00180) UniProt (by SIFTS) (Q5SIJ1) | Thermus thermophilus | |
| 2 | E (A) | 3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid | non-polymer | 178.2 | 1 | Chemie (XYN) | |||
| 3 | F, G, H, I, J... (A, B, C, D) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 19 | Chemie (MPD) | |||
| 4 | K, W (B, D) | (2Z)-3-[(carboxymethyl)sulfanyl]-2-hydroxyprop-2-enoic acid | non-polymer | 178.2 | 2 | Chemie (XYM) | |||
| 5 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 388 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143869.3 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2779.8 | |
| All* | Total formula weight | 146649.1 |
