3ARR

Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with PENTOXIFYLLINE

Summary for 3ARR

Entry DOI	10.2210/pdb3arr/pdb
Related	3ARO 3ARP 3ARQ 3ARS 3ART 3ARU 3ARV 3ARW 3ARX 3ARY 3ARZ 3AS0 3AS1 3AS2 3AS3
Descriptor	Chitinase A, 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE (3 entities in total)
Functional Keywords	tim barrel, inhibitor complex, glycosidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Vibrio harveyi
Total number of polymer chains	1
Total formula weight	64398.38
Authors	Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-11-01)
Primary citation	Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286:24312-24323, 2011 Cited by PubMed: 21531720 DOI: 10.1074/jbc.M110.183376 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation