3AMA
Protein kinase A sixfold mutant model of Aurora B with inhibitor JNJ-7706621
Summary for 3AMA
Entry DOI | 10.2210/pdb3ama/pdb |
Related | 3AMB |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, ... (4 entities in total) |
Functional Keywords | pka, protein kinase a, surrogate, jnj-7706621, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P17612 |
Total number of polymer chains | 2 |
Total formula weight | 43477.24 |
Authors | Pflug, A.,de Oliveira, T.M.,Bossemeyer, D.,Engh, R.A. (deposition date: 2010-08-18, release date: 2011-08-03, Last modification date: 2023-11-01) |
Primary citation | Pflug, A.,de Oliveira, T.M.,Bossemeyer, D.,Engh, R.A. Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase Biochem.J., 440:85-93, 2011 Cited by PubMed: 21774789DOI: 10.1042/BJ20110592 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)