3AHQ

hyperactive human Ero1

Summary for 3AHQ

• Entry DOI: 10.2210/pdb3ahq/pdb
• Related: 1RP4 3AHR
• Descriptor: ERO1-like protein alpha, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: disulfide bond, pdi, redox, hyperactive human ero1, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side: Q96HE7
• Total number of polymer chains: 1
• Total formula weight: 54958.38

Authors

Inaba, K.,Sitia, R.,Suzuki, M. (deposition date: 2010-04-26, release date: 2010-12-22, Last modification date: 2023-11-01)

• Primary citation: Inaba, K.,Masui, S.,Iida, H.,Vavassori, S.,Sitia, R.,Suzuki, M.; Crystal structures of human Ero1-alpha reveal the mechanisms of regulated and targeted oxidation of PDI; Embo J., 29:3330-3343, 2010; PubMed: 20834232; DOI: 10.1038/emboj.2010.222

Experimental method

X-RAY DIFFRACTION (2.35 Å)