3ACL
Crystal Structure of Human Pirin in complex with Triphenyl Compound
Summary for 3ACL
Entry DOI | 10.2210/pdb3acl/pdb |
Related | 1J1L |
Descriptor | Pirin, FE (II) ION, N-{[4-(benzyloxy)phenyl](methyl)-lambda~4~-sulfanylidene}-4-methylbenzenesulfonamide, ... (4 entities in total) |
Functional Keywords | cupin, inhibitor, complex, iron, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : O00625 |
Total number of polymer chains | 1 |
Total formula weight | 33443.64 |
Authors | Okumura, H.,Miyazaki, I.,Simizu, S.,Osada, H. (deposition date: 2010-01-05, release date: 2010-08-18, Last modification date: 2023-11-01) |
Primary citation | Miyazaki, I.,Simizu, S.,Okumura, H.,Takagi, S.,Osada, H. A small-molecule inhibitor shows that pirin regulates migration of melanoma cells Nat.Chem.Biol., 6:667-673, 2010 Cited by PubMed: 20711196DOI: 10.1038/nchembio.423 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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