3AAZ
Crystal structure of the humanized recombinant Fab fragment of a murine; antibody
Summary for 3AAZ
| Entry DOI | 10.2210/pdb3aaz/pdb |
| Descriptor | Humanized recombinant Fab fragment of a murine; antibody (3 entities in total) |
| Functional Keywords | antibody engineering, humanization, hwo-2 fab, immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 100005.98 |
| Authors | Streltsov, V.A. (deposition date: 2009-11-28, release date: 2010-03-02, Last modification date: 2023-11-01) |
| Primary citation | Robert, R.,Streltsov, V.A.,Newman, J.,Pearce, L.A.,Wark, K.L.,Dolezal, O. Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment. Protein Sci., 19:299-308, 2010 Cited by PubMed: 20014445DOI: 10.1002/pro.312 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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