3AAV

Bovine beta-trypsin bound to meta-diamidino schiff base copper (II) chelate

Summary for 3AAV

Entry DOI	10.2210/pdb3aav/pdb
Related	3AAS 3AAU
Descriptor	Cationic trypsin, 3,3'-[ethane-1,2-diylbis(nitrilomethylylidene)]bis(4-hydroxybenzenecarboximidamide), CALCIUM ION, ... (5 entities in total)
Functional Keywords	enzyme-inhibitor complex, coordination metal based inhibitor, hydrolase, calcium, digestion, metal-binding, protease, secreted, serine protease, zymogen
Biological source	Bos taurus (bovine)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	2
Total formula weight	47560.60
Authors	Iyaguchi, D.,Kawano, S.,Toyota, E. (deposition date: 2009-11-26, release date: 2010-04-07, Last modification date: 2023-11-01)
Primary citation	Iyaguchi, D.,Kawano, S.,Takada, K.,Toyota, E. Structural basis for the design of novel Schiff base metal chelate inhibitors of trypsin Bioorg.Med.Chem., 18:2076-2080, 2010 Cited by PubMed: 20202854 DOI: 10.1016/j.bmc.2010.02.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation