3AAJ

Crystal structure of Ca2+-bound form of des3-23ALG-2deltaGF122

Summary for 3AAJ

Entry DOI	10.2210/pdb3aaj/pdb
Related	1HQV 2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAK
Descriptor	Programmed cell death protein 6, CALCIUM ION (3 entities in total)
Functional Keywords	penta-ef-hand protein, calcium-binding protein, apoptosis, endoplasmic reticulum
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum membrane ; Peripheral membrane protein : O75340
Total number of polymer chains	2
Total formula weight	39586.30
Authors	Suzuki, H.,Inuzuka, T.,Kawasaki, M.,Shibata, H.,Wakatsuki, S.,Maki, M. (deposition date: 2009-11-19, release date: 2010-09-08, Last modification date: 2023-11-01)
Primary citation	Inuzuka, T.,Suzuki, H.,Kawasaki, M.,Shibata, H.,Wakatsuki, S.,Maki, M. Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition Bmc Struct.Biol., 10:25-25, 2010 Cited by PubMed: 20691033 DOI: 10.1186/1472-6807-10-25 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation