3A73

Crystal Structure Analysis of Human serum albumin complexed with delta 12-prostaglandin J2

Summary for 3A73

Entry DOI	10.2210/pdb3a73/pdb
Descriptor	Serum albumin, MYRISTIC ACID, (5Z,12Z,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid, ... (4 entities in total)
Functional Keywords	alpha-helical strcture, cleavage on pair of basic residues, disease mutation, disulfide bond, glycation, glycoprotein, lipid-binding, metal-binding, phosphoprotein, secreted, lipid binding protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02768
Total number of polymer chains	2
Total formula weight	136886.24
Authors	Ito, S. (deposition date: 2009-09-11, release date: 2010-01-19, Last modification date: 2023-11-01)
Primary citation	Yamaguchi, S.,Aldini, G.,Ito, S.,Morishita, N.,Shibata, T.,Vistoli, G.,Carini, M.,Uchida, K. Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146. J.Am.Chem.Soc., 132:824-832, 2010 Cited by PubMed: 20014793 DOI: 10.1021/ja908878n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation