3A4Z
Structure of cytochrome P450 Vdh mutant (Vdh-K1) obtained by directed evolution
Summary for 3A4Z
Entry DOI | 10.2210/pdb3a4z/pdb |
Related | 3A4G 3A4H 3A50 3A51 |
Descriptor | Vitamin D hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | cytochrome p450, vitamin d3 hydroxylase, hemoprotein, monooxygenase, directed evolution, oxidoreductase |
Biological source | Pseudonocardia autotrophica |
Cellular location | Cytoplasm : C4B644 |
Total number of polymer chains | 5 |
Total formula weight | 231800.79 |
Authors | Yasutake, Y.,Fujii, Y.,Cheon, W.K.,Arisawa, A.,Tamura, T. (deposition date: 2009-07-24, release date: 2010-07-28, Last modification date: 2023-11-01) |
Primary citation | Yasutake, Y.,Fujii, Y.,Nishioka, T.,Cheon, W.K.,Arisawa, A.,Tamura, T. Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase J.Biol.Chem., 285:31193-31201, 2010 Cited by PubMed: 20667833DOI: 10.1074/jbc.M110.147009 PDB entries with the same primary citation |
Experimental method |
Structure validation
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