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3A4E

Crystal structure of Human Transthyretin (E54G)

Summary for 3A4E
Entry DOI10.2210/pdb3a4e/pdb
Related3A4D 3A4F
DescriptorTransthyretin, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywordsbeta barrel, amyloid, amyloidosis, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hormone, neuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein, thyroxine
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight27879.01
Authors
Miyata, M.,Sato, T.,Nakamura, T.,Ikemizu, S.,Yamagata, Y.,Kai, H. (deposition date: 2009-07-06, release date: 2009-12-22, Last modification date: 2023-11-01)
Primary citationMiyata, M.,Sato, T.,Mizuguchi, M.,Nakamura, T.,Ikemizu, S.,Nabeshima, Y.,Susuki, S.,Suwa, Y.,Morioka, H.,Ando, Y.,Suico, M.A.,Shuto, T.,Koga, T.,Yamagata, Y.,Kai, H.
Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49:114-123, 2010
Cited by
PubMed: 19950966
DOI: 10.1021/bi901677z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

건을2024-03-27부터공개중

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