3ZNC
MURINE CARBONIC ANHYDRASE IV COMPLEXED WITH BRINZOLAMIDE
Summary for 3ZNC
Entry DOI | 10.2210/pdb3znc/pdb |
Descriptor | CARBONIC ANHYDRASE IV, ZINC ION, (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, ... (4 entities in total) |
Functional Keywords | lyase, zinc, murine, membrane, inhibitor |
Biological source | Mus musculus (house mouse) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor (By similarity): Q64444 |
Total number of polymer chains | 1 |
Total formula weight | 29939.44 |
Authors | Stams, T.,Chen, Y.,Christianson, D.W. (deposition date: 1998-02-10, release date: 1999-03-23, Last modification date: 2011-07-13) |
Primary citation | Stams, T.,Chen, Y.,Boriack-Sjodin, P.A.,Hurt, J.D.,Liao, J.,May, J.A.,Dean, T.,Laipis, P.,Silverman, D.N.,Christianson, D.W. Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination. Protein Sci., 7:556-563, 1998 Cited by PubMed: 9541386PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report