3ZMP

Src-derived peptide inhibitor complex of PTP1B

Summary for 3ZMP

Entry DOI	10.2210/pdb3zmp/pdb
Descriptor	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (3 entities in total)
Functional Keywords	hydrolase-peptide complex, enzyme inhibitors, structure-activity relationship, transferase, hydrolase/peptide
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : P18031 Cell membrane: P12931
Total number of polymer chains	4
Total formula weight	79471.99
Authors	Temmerman, K.,Pogenberg, V.,Meyer, C.,Koehn, M.,Wilmanns, M. (deposition date: 2013-02-12, release date: 2014-01-22, Last modification date: 2023-12-20)
Primary citation	Meyer, C.,Hoeger, B.,Temmerman, K.,Tatarek-Nossol, M.,Pogenberg, V.,Bernhagen, J.,Wilmanns, M.,Kapurniotu, A.,Kohn, M. Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells. Acs Chem.Biol., 9:769-, 2014 Cited by PubMed: 24387659 DOI: 10.1021/CB400903U PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.619 Å)

Structure validation