3ZMP

Src-derived peptide inhibitor complex of PTP1B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1	polymer	329	38447.8	2	UniProt (P18031) Pfam (PF00102) In PDB	HOMO SAPIENS (HUMAN)	PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B
2	C, D	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	polymer	10	1288.2	2	UniProt (P12931) In PDB	HOMO SAPIENS	SRC-DERIVED PEPTIDE, PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC
3		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B: 1 - 321 (UniProt: P18031)

PDB	External Database	Details
Met -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 215	Cys 215	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	79472.0
All*	Total formula weight	79472.0

*Water molecules are not included.