3ZHX
Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue
Summary for 3ZHX
Entry DOI | 10.2210/pdb3zhx/pdb |
Related | 3ZHY 3ZHZ 3ZI0 |
Descriptor | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl(phenylcarbonyl)amino]propyl]phosphonic acid, ... (4 entities in total) |
Functional Keywords | oxidoreductase, rv2870c, doxp/mep pathway, ispc |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 2 |
Total formula weight | 83713.79 |
Authors | Bjorkelid, C.,Jansson, A.M.,Bergfors, T.,Unge, T.,Mowbray, S.L.,Jones, T.A. (deposition date: 2012-12-30, release date: 2013-10-09, Last modification date: 2024-05-08) |
Primary citation | Jansson, A.M.,Wieckowska, A.,Bjorkelid, C.,Yahiaoui, S.,Sooriyaarachchi, S.,Lindh, M.,Bergfors, T.,Dharavath, S.,Desroses, M.,Suresh, S.,Andaloussi, M.,Nikhil, R.,Sreevalli, S.,Srinivasa, B.R.,Larhed, M.,Jones, T.A.,Karlen, A.,Mowbray, S.L. Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues. J.Med.Chem., 56:6190-, 2013 Cited by PubMed: 23819803DOI: 10.1021/JM4006498 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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