3ZG6
The novel de-long chain fatty acid function of human sirt6
Summary for 3ZG6
Entry DOI | 10.2210/pdb3zg6/pdb |
Descriptor | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6, PEPTIDE, ZINC ION, ... (6 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, sirtuin class iii, hdacs nad dependent, hydrolase/inhibitor |
Biological source | HOMO SAPIENS More |
Cellular location | Nucleus, nucleoplasm: Q8N6T7 |
Total number of polymer chains | 2 |
Total formula weight | 35317.68 |
Authors | |
Primary citation | Jiang, H.,Khan, S.,Wang, Y.,Charron, G.,He, B.,Sebastian, C.,Du, J.,Kim, R.,Ge, E.,Mostoslavsky, R.,Hang, H.C.,Hao, Q.,Lin, H. Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine Nature, 496:110-, 2013 Cited by PubMed: 23552949DOI: 10.1038/NATURE12038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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