3VON

Crystalstructure of the ubiquitin protease

Summary for 3VON

• Entry DOI: 10.2210/pdb3von/pdb
• Descriptor: Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 variant 2, Ubiquitin-conjugating enzyme E2 N (3 entities in total)
• Functional Keywords: ubiquitin protease, hydrolase-ligase complex, hydrolase/ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): Q96FW1; Nucleus: P61088
• Total number of polymer chains: 42
• Total formula weight: 742231.87

Authors

Sato, Y.,Fukai, S. (deposition date: 2012-01-30, release date: 2012-05-30, Last modification date: 2023-11-08)

• Primary citation: Sato, Y.,Yamagata, A.,Goto-Ito, S.,Kubota, K.,Miyamoto, R.,Nakada, S.,Fukai, S.; Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.; J.Biol.Chem., 287:25860-25868, 2012; PubMed: 22679021; DOI: 10.1074/jbc.M112.364752

Experimental method

X-RAY DIFFRACTION (3.15 Å)