3VON

Crystalstructure of the ubiquitin protease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016579	biological_process	protein deubiquitination
A	0016787	molecular_function	hydrolase activity
B	0000209	biological_process	protein polyubiquitination
B	0000729	biological_process	DNA double-strand break processing
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006282	biological_process	regulation of DNA repair
B	0006301	biological_process	DNA damage tolerance
B	0016567	biological_process	protein ubiquitination
B	0031371	cellular_component	ubiquitin conjugating enzyme complex
B	0031372	cellular_component	UBC13-MMS2 complex
B	0042275	biological_process	error-free postreplication DNA repair
B	0070062	cellular_component	extracellular exosome
B	0070534	biological_process	protein K63-linked ubiquitination
B	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
B	2000781	biological_process	positive regulation of double-strand break repair
C	0000151	cellular_component	ubiquitin ligase complex
C	0000166	molecular_function	nucleotide binding
C	0000209	biological_process	protein polyubiquitination
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000729	biological_process	DNA double-strand break processing
C	0003723	molecular_function	RNA binding
C	0004842	molecular_function	ubiquitin-protein transferase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006281	biological_process	DNA repair
C	0006282	biological_process	regulation of DNA repair
C	0006301	biological_process	DNA damage tolerance
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0006513	biological_process	protein monoubiquitination
C	0006974	biological_process	DNA damage response
C	0016567	biological_process	protein ubiquitination
C	0016740	molecular_function	transferase activity
C	0031371	cellular_component	ubiquitin conjugating enzyme complex
C	0031372	cellular_component	UBC13-MMS2 complex
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032991	cellular_component	protein-containing complex
C	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
C	0043130	molecular_function	ubiquitin binding
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0045739	biological_process	positive regulation of DNA repair
C	0050852	biological_process	T cell receptor signaling pathway
C	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
C	0061631	molecular_function	ubiquitin conjugating enzyme activity
C	0070062	cellular_component	extracellular exosome
C	0070534	biological_process	protein K63-linked ubiquitination
C	0097027	molecular_function	ubiquitin-protein transferase activator activity
C	0140374	biological_process	antiviral innate immune response
C	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
C	1902533	biological_process	positive regulation of intracellular signal transduction
C	1904262	biological_process	negative regulation of TORC1 signaling
C	2000781	biological_process	positive regulation of double-strand break repair
D	0000209	biological_process	protein polyubiquitination
D	0000729	biological_process	DNA double-strand break processing
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0006282	biological_process	regulation of DNA repair
D	0006301	biological_process	DNA damage tolerance
D	0016567	biological_process	protein ubiquitination
D	0031371	cellular_component	ubiquitin conjugating enzyme complex
D	0031372	cellular_component	UBC13-MMS2 complex
D	0042275	biological_process	error-free postreplication DNA repair
D	0070062	cellular_component	extracellular exosome
D	0070534	biological_process	protein K63-linked ubiquitination
D	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
D	2000781	biological_process	positive regulation of double-strand break repair
E	0000151	cellular_component	ubiquitin ligase complex
E	0000166	molecular_function	nucleotide binding
E	0000209	biological_process	protein polyubiquitination
E	0000724	biological_process	double-strand break repair via homologous recombination
E	0000729	biological_process	DNA double-strand break processing
E	0003723	molecular_function	RNA binding
E	0004842	molecular_function	ubiquitin-protein transferase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006281	biological_process	DNA repair
E	0006282	biological_process	regulation of DNA repair
E	0006301	biological_process	DNA damage tolerance
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0006513	biological_process	protein monoubiquitination
E	0006974	biological_process	DNA damage response
E	0016567	biological_process	protein ubiquitination
E	0016740	molecular_function	transferase activity
E	0031371	cellular_component	ubiquitin conjugating enzyme complex
E	0031372	cellular_component	UBC13-MMS2 complex
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032991	cellular_component	protein-containing complex
E	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
E	0043130	molecular_function	ubiquitin binding
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0045739	biological_process	positive regulation of DNA repair
E	0050852	biological_process	T cell receptor signaling pathway
E	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
E	0061631	molecular_function	ubiquitin conjugating enzyme activity
E	0070062	cellular_component	extracellular exosome
E	0070534	biological_process	protein K63-linked ubiquitination
E	0097027	molecular_function	ubiquitin-protein transferase activator activity
E	0140374	biological_process	antiviral innate immune response
E	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
E	1902533	biological_process	positive regulation of intracellular signal transduction
E	1904262	biological_process	negative regulation of TORC1 signaling
E	2000781	biological_process	positive regulation of double-strand break repair
F	0000209	biological_process	protein polyubiquitination
F	0000729	biological_process	DNA double-strand break processing
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0006282	biological_process	regulation of DNA repair
F	0006301	biological_process	DNA damage tolerance
F	0016567	biological_process	protein ubiquitination
F	0031371	cellular_component	ubiquitin conjugating enzyme complex
F	0031372	cellular_component	UBC13-MMS2 complex
F	0042275	biological_process	error-free postreplication DNA repair
F	0070062	cellular_component	extracellular exosome
F	0070534	biological_process	protein K63-linked ubiquitination
F	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
F	2000781	biological_process	positive regulation of double-strand break repair
G	0000151	cellular_component	ubiquitin ligase complex
G	0000166	molecular_function	nucleotide binding
G	0000209	biological_process	protein polyubiquitination
G	0000724	biological_process	double-strand break repair via homologous recombination
G	0000729	biological_process	DNA double-strand break processing
G	0003723	molecular_function	RNA binding
G	0004842	molecular_function	ubiquitin-protein transferase activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006281	biological_process	DNA repair
G	0006282	biological_process	regulation of DNA repair
G	0006301	biological_process	DNA damage tolerance
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006513	biological_process	protein monoubiquitination
G	0006974	biological_process	DNA damage response
G	0016567	biological_process	protein ubiquitination
G	0016740	molecular_function	transferase activity
G	0031371	cellular_component	ubiquitin conjugating enzyme complex
G	0031372	cellular_component	UBC13-MMS2 complex
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032991	cellular_component	protein-containing complex
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043130	molecular_function	ubiquitin binding
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0045739	biological_process	positive regulation of DNA repair
G	0050852	biological_process	T cell receptor signaling pathway
G	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
G	0061631	molecular_function	ubiquitin conjugating enzyme activity
G	0070062	cellular_component	extracellular exosome
G	0070534	biological_process	protein K63-linked ubiquitination
G	0097027	molecular_function	ubiquitin-protein transferase activator activity
G	0140374	biological_process	antiviral innate immune response
G	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
G	1902533	biological_process	positive regulation of intracellular signal transduction
G	1904262	biological_process	negative regulation of TORC1 signaling
G	2000781	biological_process	positive regulation of double-strand break repair
H	0016579	biological_process	protein deubiquitination
H	0016787	molecular_function	hydrolase activity
I	0000209	biological_process	protein polyubiquitination
I	0000729	biological_process	DNA double-strand break processing
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0006282	biological_process	regulation of DNA repair
I	0006301	biological_process	DNA damage tolerance
I	0016567	biological_process	protein ubiquitination
I	0031371	cellular_component	ubiquitin conjugating enzyme complex
I	0031372	cellular_component	UBC13-MMS2 complex
I	0042275	biological_process	error-free postreplication DNA repair
I	0070062	cellular_component	extracellular exosome
I	0070534	biological_process	protein K63-linked ubiquitination
I	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
I	2000781	biological_process	positive regulation of double-strand break repair
J	0000151	cellular_component	ubiquitin ligase complex
J	0000166	molecular_function	nucleotide binding
J	0000209	biological_process	protein polyubiquitination
J	0000724	biological_process	double-strand break repair via homologous recombination
J	0000729	biological_process	DNA double-strand break processing
J	0003723	molecular_function	RNA binding
J	0004842	molecular_function	ubiquitin-protein transferase activity
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006281	biological_process	DNA repair
J	0006282	biological_process	regulation of DNA repair
J	0006301	biological_process	DNA damage tolerance
J	0006511	biological_process	ubiquitin-dependent protein catabolic process
J	0006513	biological_process	protein monoubiquitination
J	0006974	biological_process	DNA damage response
J	0016567	biological_process	protein ubiquitination
J	0016740	molecular_function	transferase activity
J	0031371	cellular_component	ubiquitin conjugating enzyme complex
J	0031372	cellular_component	UBC13-MMS2 complex
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032991	cellular_component	protein-containing complex
J	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
J	0043130	molecular_function	ubiquitin binding
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0045739	biological_process	positive regulation of DNA repair
J	0050852	biological_process	T cell receptor signaling pathway
J	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
J	0061631	molecular_function	ubiquitin conjugating enzyme activity
J	0070062	cellular_component	extracellular exosome
J	0070534	biological_process	protein K63-linked ubiquitination
J	0097027	molecular_function	ubiquitin-protein transferase activator activity
J	0140374	biological_process	antiviral innate immune response
J	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
J	1902533	biological_process	positive regulation of intracellular signal transduction
J	1904262	biological_process	negative regulation of TORC1 signaling
J	2000781	biological_process	positive regulation of double-strand break repair
K	0000209	biological_process	protein polyubiquitination
K	0000729	biological_process	DNA double-strand break processing
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0006282	biological_process	regulation of DNA repair
K	0006301	biological_process	DNA damage tolerance
K	0016567	biological_process	protein ubiquitination
K	0031371	cellular_component	ubiquitin conjugating enzyme complex
K	0031372	cellular_component	UBC13-MMS2 complex
K	0042275	biological_process	error-free postreplication DNA repair
K	0070062	cellular_component	extracellular exosome
K	0070534	biological_process	protein K63-linked ubiquitination
K	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
K	2000781	biological_process	positive regulation of double-strand break repair
L	0000151	cellular_component	ubiquitin ligase complex
L	0000166	molecular_function	nucleotide binding
L	0000209	biological_process	protein polyubiquitination
L	0000724	biological_process	double-strand break repair via homologous recombination
L	0000729	biological_process	DNA double-strand break processing
L	0003723	molecular_function	RNA binding
L	0004842	molecular_function	ubiquitin-protein transferase activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006281	biological_process	DNA repair
L	0006282	biological_process	regulation of DNA repair
L	0006301	biological_process	DNA damage tolerance
L	0006511	biological_process	ubiquitin-dependent protein catabolic process
L	0006513	biological_process	protein monoubiquitination
L	0006974	biological_process	DNA damage response
L	0016567	biological_process	protein ubiquitination
L	0016740	molecular_function	transferase activity
L	0031371	cellular_component	ubiquitin conjugating enzyme complex
L	0031372	cellular_component	UBC13-MMS2 complex
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032991	cellular_component	protein-containing complex
L	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
L	0043130	molecular_function	ubiquitin binding
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0045739	biological_process	positive regulation of DNA repair
L	0050852	biological_process	T cell receptor signaling pathway
L	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
L	0061631	molecular_function	ubiquitin conjugating enzyme activity
L	0070062	cellular_component	extracellular exosome
L	0070534	biological_process	protein K63-linked ubiquitination
L	0097027	molecular_function	ubiquitin-protein transferase activator activity
L	0140374	biological_process	antiviral innate immune response
L	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
L	1902533	biological_process	positive regulation of intracellular signal transduction
L	1904262	biological_process	negative regulation of TORC1 signaling
L	2000781	biological_process	positive regulation of double-strand break repair
M	0000209	biological_process	protein polyubiquitination
M	0000729	biological_process	DNA double-strand break processing
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0006282	biological_process	regulation of DNA repair
M	0006301	biological_process	DNA damage tolerance
M	0016567	biological_process	protein ubiquitination
M	0031371	cellular_component	ubiquitin conjugating enzyme complex
M	0031372	cellular_component	UBC13-MMS2 complex
M	0042275	biological_process	error-free postreplication DNA repair
M	0070062	cellular_component	extracellular exosome
M	0070534	biological_process	protein K63-linked ubiquitination
M	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
M	2000781	biological_process	positive regulation of double-strand break repair
N	0000151	cellular_component	ubiquitin ligase complex
N	0000166	molecular_function	nucleotide binding
N	0000209	biological_process	protein polyubiquitination
N	0000724	biological_process	double-strand break repair via homologous recombination
N	0000729	biological_process	DNA double-strand break processing
N	0003723	molecular_function	RNA binding
N	0004842	molecular_function	ubiquitin-protein transferase activity
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006281	biological_process	DNA repair
N	0006282	biological_process	regulation of DNA repair
N	0006301	biological_process	DNA damage tolerance
N	0006511	biological_process	ubiquitin-dependent protein catabolic process
N	0006513	biological_process	protein monoubiquitination
N	0006974	biological_process	DNA damage response
N	0016567	biological_process	protein ubiquitination
N	0016740	molecular_function	transferase activity
N	0031371	cellular_component	ubiquitin conjugating enzyme complex
N	0031372	cellular_component	UBC13-MMS2 complex
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0032991	cellular_component	protein-containing complex
N	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
N	0043130	molecular_function	ubiquitin binding
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0045739	biological_process	positive regulation of DNA repair
N	0050852	biological_process	T cell receptor signaling pathway
N	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
N	0061631	molecular_function	ubiquitin conjugating enzyme activity
N	0070062	cellular_component	extracellular exosome
N	0070534	biological_process	protein K63-linked ubiquitination
N	0097027	molecular_function	ubiquitin-protein transferase activator activity
N	0140374	biological_process	antiviral innate immune response
N	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
N	1902533	biological_process	positive regulation of intracellular signal transduction
N	1904262	biological_process	negative regulation of TORC1 signaling
N	2000781	biological_process	positive regulation of double-strand break repair
O	0016579	biological_process	protein deubiquitination
O	0016787	molecular_function	hydrolase activity
P	0000209	biological_process	protein polyubiquitination
P	0000729	biological_process	DNA double-strand break processing
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0006282	biological_process	regulation of DNA repair
P	0006301	biological_process	DNA damage tolerance
P	0016567	biological_process	protein ubiquitination
P	0031371	cellular_component	ubiquitin conjugating enzyme complex
P	0031372	cellular_component	UBC13-MMS2 complex
P	0042275	biological_process	error-free postreplication DNA repair
P	0070062	cellular_component	extracellular exosome
P	0070534	biological_process	protein K63-linked ubiquitination
P	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
P	2000781	biological_process	positive regulation of double-strand break repair
Q	0000151	cellular_component	ubiquitin ligase complex
Q	0000166	molecular_function	nucleotide binding
Q	0000209	biological_process	protein polyubiquitination
Q	0000724	biological_process	double-strand break repair via homologous recombination
Q	0000729	biological_process	DNA double-strand break processing
Q	0003723	molecular_function	RNA binding
Q	0004842	molecular_function	ubiquitin-protein transferase activity
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006281	biological_process	DNA repair
Q	0006282	biological_process	regulation of DNA repair
Q	0006301	biological_process	DNA damage tolerance
Q	0006511	biological_process	ubiquitin-dependent protein catabolic process
Q	0006513	biological_process	protein monoubiquitination
Q	0006974	biological_process	DNA damage response
Q	0016567	biological_process	protein ubiquitination
Q	0016740	molecular_function	transferase activity
Q	0031371	cellular_component	ubiquitin conjugating enzyme complex
Q	0031372	cellular_component	UBC13-MMS2 complex
Q	0031625	molecular_function	ubiquitin protein ligase binding
Q	0032991	cellular_component	protein-containing complex
Q	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
Q	0043130	molecular_function	ubiquitin binding
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0045739	biological_process	positive regulation of DNA repair
Q	0050852	biological_process	T cell receptor signaling pathway
Q	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
Q	0061631	molecular_function	ubiquitin conjugating enzyme activity
Q	0070062	cellular_component	extracellular exosome
Q	0070534	biological_process	protein K63-linked ubiquitination
Q	0097027	molecular_function	ubiquitin-protein transferase activator activity
Q	0140374	biological_process	antiviral innate immune response
Q	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
Q	1902533	biological_process	positive regulation of intracellular signal transduction
Q	1904262	biological_process	negative regulation of TORC1 signaling
Q	2000781	biological_process	positive regulation of double-strand break repair
R	0000209	biological_process	protein polyubiquitination
R	0000729	biological_process	DNA double-strand break processing
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0006282	biological_process	regulation of DNA repair
R	0006301	biological_process	DNA damage tolerance
R	0016567	biological_process	protein ubiquitination
R	0031371	cellular_component	ubiquitin conjugating enzyme complex
R	0031372	cellular_component	UBC13-MMS2 complex
R	0042275	biological_process	error-free postreplication DNA repair
R	0070062	cellular_component	extracellular exosome
R	0070534	biological_process	protein K63-linked ubiquitination
R	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
R	2000781	biological_process	positive regulation of double-strand break repair
S	0000151	cellular_component	ubiquitin ligase complex
S	0000166	molecular_function	nucleotide binding
S	0000209	biological_process	protein polyubiquitination
S	0000724	biological_process	double-strand break repair via homologous recombination
S	0000729	biological_process	DNA double-strand break processing
S	0003723	molecular_function	RNA binding
S	0004842	molecular_function	ubiquitin-protein transferase activity
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006281	biological_process	DNA repair
S	0006282	biological_process	regulation of DNA repair
S	0006301	biological_process	DNA damage tolerance
S	0006511	biological_process	ubiquitin-dependent protein catabolic process
S	0006513	biological_process	protein monoubiquitination
S	0006974	biological_process	DNA damage response
S	0016567	biological_process	protein ubiquitination
S	0016740	molecular_function	transferase activity
S	0031371	cellular_component	ubiquitin conjugating enzyme complex
S	0031372	cellular_component	UBC13-MMS2 complex
S	0031625	molecular_function	ubiquitin protein ligase binding
S	0032991	cellular_component	protein-containing complex
S	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
S	0043130	molecular_function	ubiquitin binding
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0045739	biological_process	positive regulation of DNA repair
S	0050852	biological_process	T cell receptor signaling pathway
S	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
S	0061631	molecular_function	ubiquitin conjugating enzyme activity
S	0070062	cellular_component	extracellular exosome
S	0070534	biological_process	protein K63-linked ubiquitination
S	0097027	molecular_function	ubiquitin-protein transferase activator activity
S	0140374	biological_process	antiviral innate immune response
S	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
S	1902533	biological_process	positive regulation of intracellular signal transduction
S	1904262	biological_process	negative regulation of TORC1 signaling
S	2000781	biological_process	positive regulation of double-strand break repair
T	0000209	biological_process	protein polyubiquitination
T	0000729	biological_process	DNA double-strand break processing
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0006282	biological_process	regulation of DNA repair
T	0006301	biological_process	DNA damage tolerance
T	0016567	biological_process	protein ubiquitination
T	0031371	cellular_component	ubiquitin conjugating enzyme complex
T	0031372	cellular_component	UBC13-MMS2 complex
T	0042275	biological_process	error-free postreplication DNA repair
T	0070062	cellular_component	extracellular exosome
T	0070534	biological_process	protein K63-linked ubiquitination
T	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
T	2000781	biological_process	positive regulation of double-strand break repair
U	0000151	cellular_component	ubiquitin ligase complex
U	0000166	molecular_function	nucleotide binding
U	0000209	biological_process	protein polyubiquitination
U	0000724	biological_process	double-strand break repair via homologous recombination
U	0000729	biological_process	DNA double-strand break processing
U	0003723	molecular_function	RNA binding
U	0004842	molecular_function	ubiquitin-protein transferase activity
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006281	biological_process	DNA repair
U	0006282	biological_process	regulation of DNA repair
U	0006301	biological_process	DNA damage tolerance
U	0006511	biological_process	ubiquitin-dependent protein catabolic process
U	0006513	biological_process	protein monoubiquitination
U	0006974	biological_process	DNA damage response
U	0016567	biological_process	protein ubiquitination
U	0016740	molecular_function	transferase activity
U	0031371	cellular_component	ubiquitin conjugating enzyme complex
U	0031372	cellular_component	UBC13-MMS2 complex
U	0031625	molecular_function	ubiquitin protein ligase binding
U	0032991	cellular_component	protein-containing complex
U	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
U	0043130	molecular_function	ubiquitin binding
U	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
U	0045739	biological_process	positive regulation of DNA repair
U	0050852	biological_process	T cell receptor signaling pathway
U	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
U	0061631	molecular_function	ubiquitin conjugating enzyme activity
U	0070062	cellular_component	extracellular exosome
U	0070534	biological_process	protein K63-linked ubiquitination
U	0097027	molecular_function	ubiquitin-protein transferase activator activity
U	0140374	biological_process	antiviral innate immune response
U	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
U	1902533	biological_process	positive regulation of intracellular signal transduction
U	1904262	biological_process	negative regulation of TORC1 signaling
U	2000781	biological_process	positive regulation of double-strand break repair
V	0016579	biological_process	protein deubiquitination
V	0016787	molecular_function	hydrolase activity
W	0000209	biological_process	protein polyubiquitination
W	0000729	biological_process	DNA double-strand break processing
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0006282	biological_process	regulation of DNA repair
W	0006301	biological_process	DNA damage tolerance
W	0016567	biological_process	protein ubiquitination
W	0031371	cellular_component	ubiquitin conjugating enzyme complex
W	0031372	cellular_component	UBC13-MMS2 complex
W	0042275	biological_process	error-free postreplication DNA repair
W	0070062	cellular_component	extracellular exosome
W	0070534	biological_process	protein K63-linked ubiquitination
W	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
W	2000781	biological_process	positive regulation of double-strand break repair
X	0000151	cellular_component	ubiquitin ligase complex
X	0000166	molecular_function	nucleotide binding
X	0000209	biological_process	protein polyubiquitination
X	0000724	biological_process	double-strand break repair via homologous recombination
X	0000729	biological_process	DNA double-strand break processing
X	0003723	molecular_function	RNA binding
X	0004842	molecular_function	ubiquitin-protein transferase activity
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006281	biological_process	DNA repair
X	0006282	biological_process	regulation of DNA repair
X	0006301	biological_process	DNA damage tolerance
X	0006511	biological_process	ubiquitin-dependent protein catabolic process
X	0006513	biological_process	protein monoubiquitination
X	0006974	biological_process	DNA damage response
X	0016567	biological_process	protein ubiquitination
X	0016740	molecular_function	transferase activity
X	0031371	cellular_component	ubiquitin conjugating enzyme complex
X	0031372	cellular_component	UBC13-MMS2 complex
X	0031625	molecular_function	ubiquitin protein ligase binding
X	0032991	cellular_component	protein-containing complex
X	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
X	0043130	molecular_function	ubiquitin binding
X	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
X	0045739	biological_process	positive regulation of DNA repair
X	0050852	biological_process	T cell receptor signaling pathway
X	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
X	0061631	molecular_function	ubiquitin conjugating enzyme activity
X	0070062	cellular_component	extracellular exosome
X	0070534	biological_process	protein K63-linked ubiquitination
X	0097027	molecular_function	ubiquitin-protein transferase activator activity
X	0140374	biological_process	antiviral innate immune response
X	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
X	1902533	biological_process	positive regulation of intracellular signal transduction
X	1904262	biological_process	negative regulation of TORC1 signaling
X	2000781	biological_process	positive regulation of double-strand break repair
Y	0000209	biological_process	protein polyubiquitination
Y	0000729	biological_process	DNA double-strand break processing
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005737	cellular_component	cytoplasm
Y	0006282	biological_process	regulation of DNA repair
Y	0006301	biological_process	DNA damage tolerance
Y	0016567	biological_process	protein ubiquitination
Y	0031371	cellular_component	ubiquitin conjugating enzyme complex
Y	0031372	cellular_component	UBC13-MMS2 complex
Y	0042275	biological_process	error-free postreplication DNA repair
Y	0070062	cellular_component	extracellular exosome
Y	0070534	biological_process	protein K63-linked ubiquitination
Y	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
Y	2000781	biological_process	positive regulation of double-strand break repair
Z	0000151	cellular_component	ubiquitin ligase complex
Z	0000166	molecular_function	nucleotide binding
Z	0000209	biological_process	protein polyubiquitination
Z	0000724	biological_process	double-strand break repair via homologous recombination
Z	0000729	biological_process	DNA double-strand break processing
Z	0003723	molecular_function	RNA binding
Z	0004842	molecular_function	ubiquitin-protein transferase activity
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006281	biological_process	DNA repair
Z	0006282	biological_process	regulation of DNA repair
Z	0006301	biological_process	DNA damage tolerance
Z	0006511	biological_process	ubiquitin-dependent protein catabolic process
Z	0006513	biological_process	protein monoubiquitination
Z	0006974	biological_process	DNA damage response
Z	0016567	biological_process	protein ubiquitination
Z	0016740	molecular_function	transferase activity
Z	0031371	cellular_component	ubiquitin conjugating enzyme complex
Z	0031372	cellular_component	UBC13-MMS2 complex
Z	0031625	molecular_function	ubiquitin protein ligase binding
Z	0032991	cellular_component	protein-containing complex
Z	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
Z	0043130	molecular_function	ubiquitin binding
Z	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Z	0045739	biological_process	positive regulation of DNA repair
Z	0050852	biological_process	T cell receptor signaling pathway
Z	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
Z	0061631	molecular_function	ubiquitin conjugating enzyme activity
Z	0070062	cellular_component	extracellular exosome
Z	0070534	biological_process	protein K63-linked ubiquitination
Z	0097027	molecular_function	ubiquitin-protein transferase activator activity
Z	0140374	biological_process	antiviral innate immune response
Z	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
Z	1902533	biological_process	positive regulation of intracellular signal transduction
Z	1904262	biological_process	negative regulation of TORC1 signaling
Z	2000781	biological_process	positive regulation of double-strand break repair
a	0000209	biological_process	protein polyubiquitination
a	0000729	biological_process	DNA double-strand break processing
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005737	cellular_component	cytoplasm
a	0006282	biological_process	regulation of DNA repair
a	0006301	biological_process	DNA damage tolerance
a	0016567	biological_process	protein ubiquitination
a	0031371	cellular_component	ubiquitin conjugating enzyme complex
a	0031372	cellular_component	UBC13-MMS2 complex
a	0042275	biological_process	error-free postreplication DNA repair
a	0070062	cellular_component	extracellular exosome
a	0070534	biological_process	protein K63-linked ubiquitination
a	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
a	2000781	biological_process	positive regulation of double-strand break repair
b	0000151	cellular_component	ubiquitin ligase complex
b	0000166	molecular_function	nucleotide binding
b	0000209	biological_process	protein polyubiquitination
b	0000724	biological_process	double-strand break repair via homologous recombination
b	0000729	biological_process	DNA double-strand break processing
b	0003723	molecular_function	RNA binding
b	0004842	molecular_function	ubiquitin-protein transferase activity
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006281	biological_process	DNA repair
b	0006282	biological_process	regulation of DNA repair
b	0006301	biological_process	DNA damage tolerance
b	0006511	biological_process	ubiquitin-dependent protein catabolic process
b	0006513	biological_process	protein monoubiquitination
b	0006974	biological_process	DNA damage response
b	0016567	biological_process	protein ubiquitination
b	0016740	molecular_function	transferase activity
b	0031371	cellular_component	ubiquitin conjugating enzyme complex
b	0031372	cellular_component	UBC13-MMS2 complex
b	0031625	molecular_function	ubiquitin protein ligase binding
b	0032991	cellular_component	protein-containing complex
b	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
b	0043130	molecular_function	ubiquitin binding
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0045739	biological_process	positive regulation of DNA repair
b	0050852	biological_process	T cell receptor signaling pathway
b	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
b	0061631	molecular_function	ubiquitin conjugating enzyme activity
b	0070062	cellular_component	extracellular exosome
b	0070534	biological_process	protein K63-linked ubiquitination
b	0097027	molecular_function	ubiquitin-protein transferase activator activity
b	0140374	biological_process	antiviral innate immune response
b	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
b	1902533	biological_process	positive regulation of intracellular signal transduction
b	1904262	biological_process	negative regulation of TORC1 signaling
b	2000781	biological_process	positive regulation of double-strand break repair
c	0016579	biological_process	protein deubiquitination
c	0016787	molecular_function	hydrolase activity
d	0000209	biological_process	protein polyubiquitination
d	0000729	biological_process	DNA double-strand break processing
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0006282	biological_process	regulation of DNA repair
d	0006301	biological_process	DNA damage tolerance
d	0016567	biological_process	protein ubiquitination
d	0031371	cellular_component	ubiquitin conjugating enzyme complex
d	0031372	cellular_component	UBC13-MMS2 complex
d	0042275	biological_process	error-free postreplication DNA repair
d	0070062	cellular_component	extracellular exosome
d	0070534	biological_process	protein K63-linked ubiquitination
d	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
d	2000781	biological_process	positive regulation of double-strand break repair
e	0000151	cellular_component	ubiquitin ligase complex
e	0000166	molecular_function	nucleotide binding
e	0000209	biological_process	protein polyubiquitination
e	0000724	biological_process	double-strand break repair via homologous recombination
e	0000729	biological_process	DNA double-strand break processing
e	0003723	molecular_function	RNA binding
e	0004842	molecular_function	ubiquitin-protein transferase activity
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006281	biological_process	DNA repair
e	0006282	biological_process	regulation of DNA repair
e	0006301	biological_process	DNA damage tolerance
e	0006511	biological_process	ubiquitin-dependent protein catabolic process
e	0006513	biological_process	protein monoubiquitination
e	0006974	biological_process	DNA damage response
e	0016567	biological_process	protein ubiquitination
e	0016740	molecular_function	transferase activity
e	0031371	cellular_component	ubiquitin conjugating enzyme complex
e	0031372	cellular_component	UBC13-MMS2 complex
e	0031625	molecular_function	ubiquitin protein ligase binding
e	0032991	cellular_component	protein-containing complex
e	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
e	0043130	molecular_function	ubiquitin binding
e	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
e	0045739	biological_process	positive regulation of DNA repair
e	0050852	biological_process	T cell receptor signaling pathway
e	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
e	0061631	molecular_function	ubiquitin conjugating enzyme activity
e	0070062	cellular_component	extracellular exosome
e	0070534	biological_process	protein K63-linked ubiquitination
e	0097027	molecular_function	ubiquitin-protein transferase activator activity
e	0140374	biological_process	antiviral innate immune response
e	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
e	1902533	biological_process	positive regulation of intracellular signal transduction
e	1904262	biological_process	negative regulation of TORC1 signaling
e	2000781	biological_process	positive regulation of double-strand break repair
f	0000209	biological_process	protein polyubiquitination
f	0000729	biological_process	DNA double-strand break processing
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005737	cellular_component	cytoplasm
f	0006282	biological_process	regulation of DNA repair
f	0006301	biological_process	DNA damage tolerance
f	0016567	biological_process	protein ubiquitination
f	0031371	cellular_component	ubiquitin conjugating enzyme complex
f	0031372	cellular_component	UBC13-MMS2 complex
f	0042275	biological_process	error-free postreplication DNA repair
f	0070062	cellular_component	extracellular exosome
f	0070534	biological_process	protein K63-linked ubiquitination
f	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
f	2000781	biological_process	positive regulation of double-strand break repair
g	0000151	cellular_component	ubiquitin ligase complex
g	0000166	molecular_function	nucleotide binding
g	0000209	biological_process	protein polyubiquitination
g	0000724	biological_process	double-strand break repair via homologous recombination
g	0000729	biological_process	DNA double-strand break processing
g	0003723	molecular_function	RNA binding
g	0004842	molecular_function	ubiquitin-protein transferase activity
g	0005515	molecular_function	protein binding
g	0005524	molecular_function	ATP binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006281	biological_process	DNA repair
g	0006282	biological_process	regulation of DNA repair
g	0006301	biological_process	DNA damage tolerance
g	0006511	biological_process	ubiquitin-dependent protein catabolic process
g	0006513	biological_process	protein monoubiquitination
g	0006974	biological_process	DNA damage response
g	0016567	biological_process	protein ubiquitination
g	0016740	molecular_function	transferase activity
g	0031371	cellular_component	ubiquitin conjugating enzyme complex
g	0031372	cellular_component	UBC13-MMS2 complex
g	0031625	molecular_function	ubiquitin protein ligase binding
g	0032991	cellular_component	protein-containing complex
g	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
g	0043130	molecular_function	ubiquitin binding
g	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
g	0045739	biological_process	positive regulation of DNA repair
g	0050852	biological_process	T cell receptor signaling pathway
g	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
g	0061631	molecular_function	ubiquitin conjugating enzyme activity
g	0070062	cellular_component	extracellular exosome
g	0070534	biological_process	protein K63-linked ubiquitination
g	0097027	molecular_function	ubiquitin-protein transferase activator activity
g	0140374	biological_process	antiviral innate immune response
g	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
g	1902533	biological_process	positive regulation of intracellular signal transduction
g	1904262	biological_process	negative regulation of TORC1 signaling
g	2000781	biological_process	positive regulation of double-strand break repair
h	0000209	biological_process	protein polyubiquitination
h	0000729	biological_process	DNA double-strand break processing
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005737	cellular_component	cytoplasm
h	0006282	biological_process	regulation of DNA repair
h	0006301	biological_process	DNA damage tolerance
h	0016567	biological_process	protein ubiquitination
h	0031371	cellular_component	ubiquitin conjugating enzyme complex
h	0031372	cellular_component	UBC13-MMS2 complex
h	0042275	biological_process	error-free postreplication DNA repair
h	0070062	cellular_component	extracellular exosome
h	0070534	biological_process	protein K63-linked ubiquitination
h	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
h	2000781	biological_process	positive regulation of double-strand break repair
i	0000151	cellular_component	ubiquitin ligase complex
i	0000166	molecular_function	nucleotide binding
i	0000209	biological_process	protein polyubiquitination
i	0000724	biological_process	double-strand break repair via homologous recombination
i	0000729	biological_process	DNA double-strand break processing
i	0003723	molecular_function	RNA binding
i	0004842	molecular_function	ubiquitin-protein transferase activity
i	0005515	molecular_function	protein binding
i	0005524	molecular_function	ATP binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006281	biological_process	DNA repair
i	0006282	biological_process	regulation of DNA repair
i	0006301	biological_process	DNA damage tolerance
i	0006511	biological_process	ubiquitin-dependent protein catabolic process
i	0006513	biological_process	protein monoubiquitination
i	0006974	biological_process	DNA damage response
i	0016567	biological_process	protein ubiquitination
i	0016740	molecular_function	transferase activity
i	0031371	cellular_component	ubiquitin conjugating enzyme complex
i	0031372	cellular_component	UBC13-MMS2 complex
i	0031625	molecular_function	ubiquitin protein ligase binding
i	0032991	cellular_component	protein-containing complex
i	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
i	0043130	molecular_function	ubiquitin binding
i	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
i	0045739	biological_process	positive regulation of DNA repair
i	0050852	biological_process	T cell receptor signaling pathway
i	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
i	0061631	molecular_function	ubiquitin conjugating enzyme activity
i	0070062	cellular_component	extracellular exosome
i	0070534	biological_process	protein K63-linked ubiquitination
i	0097027	molecular_function	ubiquitin-protein transferase activator activity
i	0140374	biological_process	antiviral innate immune response
i	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
i	1902533	biological_process	positive regulation of intracellular signal transduction
i	1904262	biological_process	negative regulation of TORC1 signaling
i	2000781	biological_process	positive regulation of double-strand break repair
j	0016579	biological_process	protein deubiquitination
j	0016787	molecular_function	hydrolase activity
k	0000209	biological_process	protein polyubiquitination
k	0000729	biological_process	DNA double-strand break processing
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005737	cellular_component	cytoplasm
k	0006282	biological_process	regulation of DNA repair
k	0006301	biological_process	DNA damage tolerance
k	0016567	biological_process	protein ubiquitination
k	0031371	cellular_component	ubiquitin conjugating enzyme complex
k	0031372	cellular_component	UBC13-MMS2 complex
k	0042275	biological_process	error-free postreplication DNA repair
k	0070062	cellular_component	extracellular exosome
k	0070534	biological_process	protein K63-linked ubiquitination
k	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
k	2000781	biological_process	positive regulation of double-strand break repair
l	0000151	cellular_component	ubiquitin ligase complex
l	0000166	molecular_function	nucleotide binding
l	0000209	biological_process	protein polyubiquitination
l	0000724	biological_process	double-strand break repair via homologous recombination
l	0000729	biological_process	DNA double-strand break processing
l	0003723	molecular_function	RNA binding
l	0004842	molecular_function	ubiquitin-protein transferase activity
l	0005515	molecular_function	protein binding
l	0005524	molecular_function	ATP binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006281	biological_process	DNA repair
l	0006282	biological_process	regulation of DNA repair
l	0006301	biological_process	DNA damage tolerance
l	0006511	biological_process	ubiquitin-dependent protein catabolic process
l	0006513	biological_process	protein monoubiquitination
l	0006974	biological_process	DNA damage response
l	0016567	biological_process	protein ubiquitination
l	0016740	molecular_function	transferase activity
l	0031371	cellular_component	ubiquitin conjugating enzyme complex
l	0031372	cellular_component	UBC13-MMS2 complex
l	0031625	molecular_function	ubiquitin protein ligase binding
l	0032991	cellular_component	protein-containing complex
l	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
l	0043130	molecular_function	ubiquitin binding
l	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
l	0045739	biological_process	positive regulation of DNA repair
l	0050852	biological_process	T cell receptor signaling pathway
l	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
l	0061631	molecular_function	ubiquitin conjugating enzyme activity
l	0070062	cellular_component	extracellular exosome
l	0070534	biological_process	protein K63-linked ubiquitination
l	0097027	molecular_function	ubiquitin-protein transferase activator activity
l	0140374	biological_process	antiviral innate immune response
l	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
l	1902533	biological_process	positive regulation of intracellular signal transduction
l	1904262	biological_process	negative regulation of TORC1 signaling
l	2000781	biological_process	positive regulation of double-strand break repair
m	0000209	biological_process	protein polyubiquitination
m	0000729	biological_process	DNA double-strand break processing
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005737	cellular_component	cytoplasm
m	0006282	biological_process	regulation of DNA repair
m	0006301	biological_process	DNA damage tolerance
m	0016567	biological_process	protein ubiquitination
m	0031371	cellular_component	ubiquitin conjugating enzyme complex
m	0031372	cellular_component	UBC13-MMS2 complex
m	0042275	biological_process	error-free postreplication DNA repair
m	0070062	cellular_component	extracellular exosome
m	0070534	biological_process	protein K63-linked ubiquitination
m	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
m	2000781	biological_process	positive regulation of double-strand break repair
n	0000151	cellular_component	ubiquitin ligase complex
n	0000166	molecular_function	nucleotide binding
n	0000209	biological_process	protein polyubiquitination
n	0000724	biological_process	double-strand break repair via homologous recombination
n	0000729	biological_process	DNA double-strand break processing
n	0003723	molecular_function	RNA binding
n	0004842	molecular_function	ubiquitin-protein transferase activity
n	0005515	molecular_function	protein binding
n	0005524	molecular_function	ATP binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006281	biological_process	DNA repair
n	0006282	biological_process	regulation of DNA repair
n	0006301	biological_process	DNA damage tolerance
n	0006511	biological_process	ubiquitin-dependent protein catabolic process
n	0006513	biological_process	protein monoubiquitination
n	0006974	biological_process	DNA damage response
n	0016567	biological_process	protein ubiquitination
n	0016740	molecular_function	transferase activity
n	0031371	cellular_component	ubiquitin conjugating enzyme complex
n	0031372	cellular_component	UBC13-MMS2 complex
n	0031625	molecular_function	ubiquitin protein ligase binding
n	0032991	cellular_component	protein-containing complex
n	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
n	0043130	molecular_function	ubiquitin binding
n	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
n	0045739	biological_process	positive regulation of DNA repair
n	0050852	biological_process	T cell receptor signaling pathway
n	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
n	0061631	molecular_function	ubiquitin conjugating enzyme activity
n	0070062	cellular_component	extracellular exosome
n	0070534	biological_process	protein K63-linked ubiquitination
n	0097027	molecular_function	ubiquitin-protein transferase activator activity
n	0140374	biological_process	antiviral innate immune response
n	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
n	1902533	biological_process	positive regulation of intracellular signal transduction
n	1904262	biological_process	negative regulation of TORC1 signaling
n	2000781	biological_process	positive regulation of double-strand break repair
o	0000209	biological_process	protein polyubiquitination
o	0000729	biological_process	DNA double-strand break processing
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005737	cellular_component	cytoplasm
o	0006282	biological_process	regulation of DNA repair
o	0006301	biological_process	DNA damage tolerance
o	0016567	biological_process	protein ubiquitination
o	0031371	cellular_component	ubiquitin conjugating enzyme complex
o	0031372	cellular_component	UBC13-MMS2 complex
o	0042275	biological_process	error-free postreplication DNA repair
o	0070062	cellular_component	extracellular exosome
o	0070534	biological_process	protein K63-linked ubiquitination
o	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
o	2000781	biological_process	positive regulation of double-strand break repair
p	0000151	cellular_component	ubiquitin ligase complex
p	0000166	molecular_function	nucleotide binding
p	0000209	biological_process	protein polyubiquitination
p	0000724	biological_process	double-strand break repair via homologous recombination
p	0000729	biological_process	DNA double-strand break processing
p	0003723	molecular_function	RNA binding
p	0004842	molecular_function	ubiquitin-protein transferase activity
p	0005515	molecular_function	protein binding
p	0005524	molecular_function	ATP binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0006281	biological_process	DNA repair
p	0006282	biological_process	regulation of DNA repair
p	0006301	biological_process	DNA damage tolerance
p	0006511	biological_process	ubiquitin-dependent protein catabolic process
p	0006513	biological_process	protein monoubiquitination
p	0006974	biological_process	DNA damage response
p	0016567	biological_process	protein ubiquitination
p	0016740	molecular_function	transferase activity
p	0031371	cellular_component	ubiquitin conjugating enzyme complex
p	0031372	cellular_component	UBC13-MMS2 complex
p	0031625	molecular_function	ubiquitin protein ligase binding
p	0032991	cellular_component	protein-containing complex
p	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
p	0043130	molecular_function	ubiquitin binding
p	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
p	0045739	biological_process	positive regulation of DNA repair
p	0050852	biological_process	T cell receptor signaling pathway
p	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
p	0061631	molecular_function	ubiquitin conjugating enzyme activity
p	0070062	cellular_component	extracellular exosome
p	0070534	biological_process	protein K63-linked ubiquitination
p	0097027	molecular_function	ubiquitin-protein transferase activator activity
p	0140374	biological_process	antiviral innate immune response
p	1902523	biological_process	positive regulation of protein K63-linked ubiquitination
p	1902533	biological_process	positive regulation of intracellular signal transduction
p	1904262	biological_process	negative regulation of TORC1 signaling
p	2000781	biological_process	positive regulation of double-strand break repair

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNVdkl.GrICLdiL

Chain	Residue	Details
b	TYR76-LEU91

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	Region: {"description":"Ubiquitin-conjugating enzyme E2 binding","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	102
Details	Region: {"description":"Free ubiquitin binding","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22367539","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4DHZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	42
Details	Region: {"description":"Ubiquitin-conjugating enzyme E2 binding","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22367539","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4DHZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Active site: {"evidences":[{"source":"PubMed","id":"22367539","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4DHZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18954305","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Active site: {"evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18954305","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	21
Details	Site: {"description":"Interacts with free ubiquitin","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Site: {"description":"Interacts with free ubiquitin","evidences":[{"source":"PubMed","id":"22325355","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22367539","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4DHZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	18
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	18
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	36
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15)","evidences":[{"source":"PubMed","id":"16112642","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16122702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	730
Details	Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---