3VG9
Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 2.7 A resolution
Summary for 3VG9
Entry DOI | 10.2210/pdb3vg9/pdb |
Related | 3VGA |
Descriptor | Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ... (7 entities in total) |
Functional Keywords | 7 transmembrane receptor, signal transduction, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 3 |
Total formula weight | 86917.91 |
Authors | Hino, T.,Arakawa, T.,Iwanari, H.,Yurugi-Kobayashi, T.,Ikeda-Suno, C.,Nakada-Nakura, Y.,Kusano-Arai, O.,Weyand, S.,Shimamura, T.,Nomura, N.,Cameron, A.D.,Kobayashi, T.,Hamakubo, T.,Iwata, S.,Murata, T. (deposition date: 2011-08-04, release date: 2012-02-01, Last modification date: 2023-11-08) |
Primary citation | Hino, T.,Arakawa, T.,Iwanari, H.,Yurugi-Kobayashi, T.,Ikeda-Suno, C.,Nakada-Nakura, Y.,Kusano-Arai, O.,Weyand, S.,Shimamura, T.,Nomura, N.,Cameron, A.D.,Kobayashi, T.,Hamakubo, T.,Iwata, S.,Murata, T. G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody Nature, 482:237-240, 2012 Cited by PubMed: 22286059DOI: 10.1038/nature10750 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report