3VD8
Crystal structure of human AIM2 PYD domain with MBP fusion
Summary for 3VD8
Entry DOI | 10.2210/pdb3vd8/pdb |
Related PRD ID | PRD_900010 |
Descriptor | Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | mbp/pyd/dd, signal transduction, inflammasome, sugar binding protein, signaling protein |
Biological source | Escherichia coli (human) More |
Total number of polymer chains | 1 |
Total formula weight | 55044.66 |
Authors | Jin, T.C.,Perry, A.,Smith, P.,Xiao, T.S. (deposition date: 2012-01-04, release date: 2013-01-16, Last modification date: 2023-09-13) |
Primary citation | Jin, T.,Perry, A.,Smith, P.,Jiang, J.,Xiao, T.S. Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288:13225-13235, 2013 Cited by PubMed: 23530044DOI: 10.1074/jbc.M113.468033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.0685 Å) |
Structure validation
Download full validation report