3VD8
Crystal structure of human AIM2 PYD domain with MBP fusion
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltose-binding periplasmic protein, Interferon-inducible protein AIM2 | polymer | 489 | 53973.4 | 1 | UniProt (P0AEY0) UniProt (O14862) Pfam (PF01547) Pfam (PF02758) In PDB | Escherichia coli (human) | MBP, MMBP, Maltodextrin-binding protein, Absent in melanoma 2 |
2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 666.6 | 1 | In PDB BIRD (PRD_900010) GlyTouCan (G87171PZ) | alpha-maltotetraose | ||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
4 | A | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
5 | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A: 1 - 358 (UniProt: P0AEY0)
A: 1001 - 1107 (UniProt: O14862)
PDB | External Database | Details |
---|---|---|
Met 0 | - | expression tag |
Ala 82 | Asp 108 | engineered mutation |
Ala 83 | Lys 109 | engineered mutation |
Ala 172 | Glu 198 | engineered mutation |
Ala 173 | Asn 199 | engineered mutation |
Ala 239 | Lys 265 | engineered mutation |
Ala 359 | - | linker |
Ala 360 | - | linker |
Leu 361 | - | linker |
Ala 362 | - | linker |
Ala 363 | - | linker |
Ala 364 | - | linker |
Gln 365 | - | linker |
Thr 366 | - | linker |
Asn 367 | - | linker |
Ala 368 | - | linker |
Val 369 | - | linker |
Asp 370 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 1108 | - | expression tag |
Ala 1109 | - | expression tag |
Ala 1110 | - | expression tag |
Leu 1111 | - | expression tag |
Glu 1112 | - | expression tag |
His 1113 | - | expression tag |
His 1114 | - | expression tag |
His 1115 | - | expression tag |
His 1116 | - | expression tag |
His 1117 | - | expression tag |
His 1118 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 53973.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 666.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 404.7 | |
All* | Total formula weight | 55044.7 |