3V7X
Complex of human carbonic anhydrase II with N-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide
Summary for 3V7X
Entry DOI | 10.2210/pdb3v7x/pdb |
Related | 3VBD |
Descriptor | Carbonic anhydrase 2, ZINC ION, N-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide, ... (6 entities in total) |
Functional Keywords | lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 31334.97 |
Authors | Mader, P.,Brynda, J.,Rezacova, P. (deposition date: 2011-12-22, release date: 2012-04-04, Last modification date: 2023-09-13) |
Primary citation | Gitto, R.,Damiano, F.M.,Mader, P.,De Luca, L.,Ferro, S.,Supuran, C.T.,Vullo, D.,Brynda, J.,Rezacova, P.,Chimirri, A. Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors. J.Med.Chem., 55:3891-3899, 2012 Cited by PubMed: 22443141DOI: 10.1021/jm300112w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.03 Å) |
Structure validation
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