3V7K

Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex

Summary for 3V7K

• Entry DOI: 10.2210/pdb3v7k/pdb
• Related: 3V7J 3V7L
• Descriptor: DNA polymerase beta, DNA (5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*AP*AP*CP*TP*CP*AP*CP*AP*A)-3'), ... (5 entities in total)
• Functional Keywords: protein-dna complex, repair polymerase, transferase-dna complex, transferase/dna
• Biological source: Rattus norvegicus (rat)
• Cellular location: Nucleus: P06766
• Total number of polymer chains: 3
• Total formula weight: 44927.19

Authors

Rangarajan, S.,Jaeger, J. (deposition date: 2011-12-21, release date: 2013-01-16, Last modification date: 2024-02-28)

• Primary citation: Rangarajan, S.,Gridley, C.L.,Firbank, S.,Dalal, S.,Sweasy, J.B.,Jaeger, J.; Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain; To be Published,

Experimental method

X-RAY DIFFRACTION (2.271 Å)