3V7A

Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

Summary for 3V7A

• Entry DOI: 10.2210/pdb3v7a/pdb
• Related: 3ONU
• Descriptor: 5B18 heavy chain, 5B18 kappa chain, Capsid (3 entities in total)
• Functional Keywords: virus, protein-fab complex, broadly-reactive antibody, immune system
• Biological source: Human calicivirus; More
• Total number of polymer chains: 6
• Total formula weight: 163976.75

Authors

Hansman, G.S.,Mclellan, J.S.,Kwong, P.D. (deposition date: 2011-12-20, release date: 2012-02-08, Last modification date: 2023-09-13)

• Primary citation: Hansman, G.S.,Taylor, D.W.,McLellan, J.S.,Smith, T.J.,Georgiev, I.,Tame, J.R.,Park, S.Y.,Yamazaki, M.,Gondaira, F.,Miki, M.,Katayama, K.,Murata, K.,Kwong, P.D.; Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle.; J.Virol., 86:3635-3646, 2012; PubMed: 22278249; DOI: 10.1128/JVI.06868-11

Experimental method

X-RAY DIFFRACTION (3.297 Å)