3V72
Crystal Structure of Rat DNA polymerase beta Mutator E295K: Enzyme-dsDNA
Summary for 3V72
Entry DOI | 10.2210/pdb3v72/pdb |
Related | 3V73 |
Descriptor | DNA polymerase beta, DNA 5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3', DNA 5'-D(P*AP*AP*AP*CP*TP*CP*AP*CP*AP*T)-3', ... (6 entities in total) |
Functional Keywords | dna repair polymerase, e295k, mutator, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Nucleus: P06766 |
Total number of polymer chains | 3 |
Total formula weight | 43984.37 |
Authors | Gridley, C.L.,Jaeger, J. (deposition date: 2011-12-20, release date: 2012-07-04, Last modification date: 2024-02-28) |
Primary citation | Li, Y.,Gridley, C.L.,Jaeger, J.,Sweasy, J.B.,Schlick, T. Unfavorable Electrostatic and Steric Interactions in DNA Polymerase beta E295K Mutant Interfere with the Enzyme s Pathway J.Am.Chem.Soc., 134:9999-10010, 2012 Cited by PubMed: 22651551DOI: 10.1021/ja300361r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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