3V3L
Crystal structure of human RNF146 WWE domain in complex with iso-ADPRibose
Summary for 3V3L
Entry DOI | 10.2210/pdb3v3l/pdb |
Descriptor | E3 ubiquitin-protein ligase RNF146, 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate) (3 entities in total) |
Functional Keywords | ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: Q9NTX7 |
Total number of polymer chains | 2 |
Total formula weight | 21629.09 |
Authors | |
Primary citation | Wang, Z.,Michaud, G.A.,Cheng, Z.,Zhang, Y.,Hinds, T.R.,Fan, E.,Cong, F.,Xu, W. Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination. Genes Dev., 26:235-240, 2012 Cited by PubMed: 22267412DOI: 10.1101/gad.182618.111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report