3V2B
Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose
Replaces: 3KH6Summary for 3V2B
Entry DOI | 10.2210/pdb3v2b/pdb |
Descriptor | Poly [ADP-ribose] polymerase 15, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, poly (adp-ribose) polymerase, adp-ribose, bal3, b-aggressive lymphoma protein 3, glycosyltransferase, nucleus, transcription, transcription regulation, transferase, adp-ribosylation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Probable): Q460N3 |
Total number of polymer chains | 1 |
Total formula weight | 22149.92 |
Authors | Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Kotzcsh, A.,Kraulis, P.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van den berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-12, release date: 2011-12-21, Last modification date: 2024-05-29) |
Primary citation | Forst, A.H.,Karlberg, T.,Herzog, N.,Thorsell, A.G.,Gross, A.,Feijs, K.L.,Verheugd, P.,Kursula, P.,Nijmeijer, B.,Kremmer, E.,Kleine, H.,Ladurner, A.G.,Schuler, H.,Luscher, B. Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains. Structure, 21:462-475, 2013 Cited by PubMed: 23473667DOI: 10.1016/j.str.2012.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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