3V2B

Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose

Replaces:  3KH6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Poly [ADP-ribose] polymerase 15	polymer	199	21590.6	1	UniProt (Q460N3) Pfam (PF01661) In PDB	Homo sapiens (human)	PARP-15, B-aggressive lymphoma protein 3
2	A	[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE	non-polymer		559.3	1	Chemie (AR6)
3		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 273 - 448 (UniProt: Q460N3)

PDB	External Database	Details
Met 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
Ser 257	-	expression tag
Ser 258	-	expression tag
Gly 259	-	expression tag
Val 260	-	expression tag
Asp 261	-	expression tag
Leu 262	-	expression tag
Gly 263	-	expression tag
Thr 264	-	expression tag
Glu 265	-	expression tag
Asn 266	-	expression tag
Leu 267	-	expression tag
Tyr 268	-	expression tag
Phe 269	-	expression tag
Gln 270	-	expression tag
Ser 271	-	expression tag
Met 272	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21590.6
Non-Polymers*	Number of molecules	1
	Total formula weight	559.3
All*	Total formula weight	22149.9

*Water molecules are not included.