3V0C

4.3 angstrom crystal structure of an inactive BoNT/A (E224Q/R363A/Y366F)

Summary for 3V0C

• Entry DOI: 10.2210/pdb3v0c/pdb
• Descriptor: BoNT/A, ZINC ION (2 entities in total)
• Functional Keywords: botulinum neurotoxin, toxin, neurotoxin associated protein, progenitor toxin complex, vhh bound interlocked complex, ntnha
• Biological source: Clostridium botulinum
• Total number of polymer chains: 1
• Total formula weight: 151264.13

Authors

Gu, S.,Rumpel, S.,Zhou, J.,Strotmeier, J.,Bigalke, H.,Perry, K.,Shoemaker, C.B.,Rummel, A.,Jin, R. (deposition date: 2011-12-07, release date: 2012-03-14, Last modification date: 2023-09-13)

• Primary citation: Gu, S.,Rumpel, S.,Zhou, J.,Strotmeier, J.,Bigalke, H.,Perry, K.,Shoemaker, C.B.,Rummel, A.,Jin, R.; Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.; Science, 335:977-981, 2012; PubMed: 22363010; DOI: 10.1126/science.1214270

Experimental method

X-RAY DIFFRACTION (4.3 Å)