3UXO
Crystal Structure of Rat DNA Polymerase Beta Mutator I260Q Apoenzyme
Summary for 3UXO
| Entry DOI | 10.2210/pdb3uxo/pdb |
| Related | 3UXN 3UXP |
| Descriptor | DNA polymerase beta (2 entities in total) |
| Functional Keywords | dna polymerase beta, ber, transferase, lyase |
| Biological source | Rattus norvegicus (brown rat,rat,rats) |
| Cellular location | Nucleus: P06766 |
| Total number of polymer chains | 2 |
| Total formula weight | 76807.47 |
| Authors | Gridley, C.L.,Jaeger, J. (deposition date: 2011-12-05, release date: 2012-12-05, Last modification date: 2024-02-28) |
| Primary citation | Gridley, C.L.,Rangarajan, S.,Firbank, S.,Dalal, S.,Sweasy, J.B.,Jaeger, J. Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta. Biochemistry, 52:4422-4432, 2013 Cited by PubMed: 23651085DOI: 10.1021/bi301368f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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