3UIK

crystal structure of human Survivin mutant K62Y/H80W in complex with H3(1-10) peptide

Summary for 3UIK

Entry DOI	10.2210/pdb3uik/pdb
Related	3UIG 3UIH 3UII 3UIJ
Descriptor	Baculoviral IAP repeat-containing protein 5, histone H3(1-10) peptide, ZINC ION (3 entities in total)
Functional Keywords	bir domain, mitosis, t3 phosphorylated h3 binding, smac/diablo binding, apoptosis-apoptosis inhibitor complex, apoptosis/apoptosis inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O15392
Total number of polymer chains	4
Total formula weight	35539.17
Authors	Du, J.,Patel, D.J. (deposition date: 2011-11-04, release date: 2012-02-01, Last modification date: 2023-09-13)
Primary citation	Du, J.,Kelly, A.E.,Funabiki, H.,Patel, D.J. Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin. Structure, 20:185-195, 2012 Cited by PubMed: 22244766 DOI: 10.1016/j.str.2011.12.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.701 Å)

Structure validation