3U8L

Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3570 (1-(5-phenylpyridin-3-yl)-1,4-diazepane)

Summary for 3U8L

Entry DOI	10.2210/pdb3u8l/pdb
Related	1UV6 1UW6 3U8J 3U8K 3U8M 3U8N
Descriptor	Acetylcholine-binding protein, 1-(5-phenylpyridin-3-yl)-1,4-diazepane, SULFATE ION, ... (4 entities in total)
Functional Keywords	lymnaea stagnalis, agonist, ligand-bindig domain, acetylcholine, acetylcholine-binding protein, acetylcholine-binding protein-agonist complex, acetylcholine-binding protein/agonist
Biological source	Lymnaea stagnalis (Great pond snail)
Cellular location	Secreted: P58154
Total number of polymer chains	10
Total formula weight	242460.21
Authors	Rohde, L.A.H.,Ahring, P.K.,Jensen, M.L.,Nielsen, E.O.,Peters, D.,Helgstrand, C.,Krintel, C.,Harpsoe, K.,Gajhede, M.,Kastrup, J.S.,Balle, T. (deposition date: 2011-10-17, release date: 2011-12-14, Last modification date: 2023-09-13)
Primary citation	Rohde, L.A.,Ahring, P.K.,Jensen, M.L.,Nielsen, E.,Peters, D.,Helgstrand, C.,Krintel, C.,Harpse, K.,Gajhede, M.,Kastrup, J.S.,Balle, T. Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed. J.Biol.Chem., 287:4248-4259, 2012 Cited by PubMed: 22170047 DOI: 10.1074/jbc.M111.292243 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation